Cannabis Effects on Antiretroviral Therapy Pharmacokinetics and Neurotoxicity
Status:
Recruiting
Trial end date:
2025-04-30
Target enrollment:
Participant gender:
Summary
This study will address whether cannabis affects antiretroviral therapy (ART) drug
concentrations, mood, and thinking. The project will have two phases. Phase 1 is an
observational study, in which 120 people will be assessed to evaluate the effects of chronic
cannabis use on ART drug concentrations, mood, and thinking. In Phase 2, the study will
administer cannabis (or placebo) to 40 people to examine its acute effects on ART drug
concentrations.