Cannabioids as a New Intervention for Amphetamine Dependence
Status:
Withdrawn
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
Addiction to amphetamine is characterized by alternating phases of intoxication and short
abstinence, followed by recurrent drug-craving episodes which result in distress and relapse.
Addiction involves a number of neurotransmission systems, including the endocannabinoid
system (ECBS). It has been demonstarted that cannabidioids can have physiological, anxiolytic
and neuroprotective properties. It has been shown to have multiple therapeutic properties for
treating anxiety, schizophrenia and interestingly cannabinoids have been shown to be
potentially helpful in treating addiction, due to their effects on various neuronal circuits
involved in this disorder.
The investigators overall hypothesis is that cannabinoids are an interesting pharmacological
contender to decrease amphetamine craving and treat amphetamine addiction.