Overview

Canakinumab in Covid-19 Cardiac Injury (The Three C Study)

Status:
Completed
Trial end date:
2021-04-01
Target enrollment:
Participant gender:
Summary
TThe purpose of this prospective, Phase 2, single center, blinded, randomized controlled study is to demonstrate as a proof of concept that early treatment with canakinumab prevents progressive heart and respiratory failure in patients with COVID-19 infection. These results will lead to and inform a Phase III randomized placebo-controlled trial.
Phase:
Phase 2
Details
Lead Sponsor:
The Cleveland Clinic
Collaborator:
Novartis
Treatments:
Antibodies, Monoclonal