Can the Prophylactic Administration of Tranexamic Acid Reduce Blood Loss After Robotic-assisted Radical Prostatectomy?
Status:
Recruiting
Trial end date:
2022-03-30
Target enrollment:
Participant gender:
Summary
The prophylactic administration of tranexamic acid reduces blood loss during procedures at
high risk of perioperative bleeding. Several studies in neurosurgery, cardiac surgery, and
orthopedics confirm this finding. The aim of this study is to evaluate the effect of
tranexamic acid on peri-and postoperative blood loss and incidence and severity of
postoperative complications. A prospective, double-blind, randomized study is conducted to
evaluate the effect on several parameters.
Based on pilot study data the investigators decided to include 200 patients in the period
from February 2020 to December 2021. The patients will be randomly assigned to study and
control groups of 100 patients each. The minimum follow-up will be 3 months.