Can Vitamin D Supplementation Improve Hepatitis C Cure Rates
Status:
Completed
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
Evidence suggests that vitamin D may be directly or indirectly a co-factor for the efficacy
of Hepatitis C virus, (HCV), antiviral therapies. The level of vitamin D necessary for
optimum immune function is ill defined and many of those with HCV infection in Scotland are
below these levels. Vitamin D is a cheap and safe medication, so its addition to anti-viral
therapy should be highly cost-effective even if only a modest increase in SVR was achieved.
Given the Scottish HCV epidemic, the world leading government response to it and the
nationally low vitamin D levels, Scotland is perfectly placed to answer this question.
Therefore the investigators hypothesize that vitamin D supplementation will improve SVR and
propose a randomised controlled trial to test this hypothesis. The anticipated end of study
date for this study is April 2015
Phase:
Phase 3
Details
Lead Sponsor:
University of Dundee
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins