Can Addition of Doxycycline Perioperatively Reduce Propionibacterium Acnes in Shoulder Arthroplasty?
Status:
Completed
Trial end date:
2017-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to investigate antibiotic treatment to target bacteria about the
shoulder. This bacteria, Propionibacterium acnes, is detected in many revision shoulder
surgeries and is thought to contribute to periprosthetic joint infections, pain, and failure
of total shoulder arthroplasty as well as other shoulder surgeries. This study is
investigating adding an FDA approved antibiotic that is commonly used for treatment of this
bacteria and many common infections. The investigators will take intraoperative cultures to
look for the presence or absence of specific bacteria. The investigators are conducting this
trial to see if adding another antibiotic to specifically target this common bacteria found
around the shoulder will be effective.