Overview

Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases

Status:
Recruiting
Trial end date:
2031-12-01
Target enrollment:
Participant gender:
Summary
The hypothesis for this study is that a preparative regimen that maximizes host immunosuppression without myeloablation will be well tolerated and sufficient for engraftment of donor hematopoietic cells. It is also to determine major toxicities from these conditioning regimens, within the first 100 days after transplantation.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Collaborator:
St. Louis Children's Hospital
Treatments:
Alemtuzumab
Fludarabine
Fludarabine phosphate
Hydroxyurea
Melphalan
Thiotepa
Vidarabine