Overview

Calcium Dobesilate Versus Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome

Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
0
Participant gender:
Female
Summary
The purpose of this study is to compare the effect of oral Calcium Dobesilate to oral Cabergoline in the prevention of ovarian hyperstimulation syndrome (OHSS) in high-risk women underwent intracytoplasmic sperm injection (ICSI).
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Benha University
Treatments:
Cabergoline
Calcium
Calcium Dobesilate
Calcium, Dietary
Criteria
Patients enrolled in the study were infertile women undergoing ICSI with one of the
following criteria: previous episodes of OHSS, polycystic ovaries (i.e., > 24 antral
follicles present on baseline ultrasound examination), high AMH (> 3.0 ng/mL), large number
of small follicles (8 to 12 mm) seen on ultrasound during ovarian stimulation, high s.E2 at
hCG trigger (E2 >3000 pg/ml or rapidly rising s.E2), presence of > 20 follicles by
ultrasound on day of retrieval or large number of oocytes retrieved (> 20).

Exclusion Criteria:

- None