Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating Patients With Prostate Cancer
Status:
Terminated
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
This phase I/II trial studies the side effects and best dose of calcitriol when given in
combination with ketoconazole and therapeutic hydrocortisone and to see how well it works in
treating patients with prostate cancer. Calcitriol may help prostate cancer cells become more
like normal cells and grow and spread more slowly. Ketoconazole and therapeutic
hydrocortisone may help calcitriol work better by making tumor cells more sensitive to the
drug. Giving calcitriol together with ketoconazole and therapeutic hydrocortisone may be a
better treatment for prostate cancer.