Calcitriol, Ketoconazole, and Dexamethasone in Treating Patients With Metastatic or Unresectable Solid Tumors
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Calcitriol may cause solid tumor cells to look more like normal cells, and to grow
and spread more slowly. Ketoconazole and dexamethasone may help calcitriol work better by
making tumor cells more sensitive to the drug. Giving calcitriol together with ketoconazole
and dexamethasone may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of calcitriol when
given together with ketoconazole and dexamethasone in treating patients with metastatic or
unresectable solid tumors.