Caesarean and Corticotherapy

• Status: Completed
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: Female

Summary

Comparison of two randomized group :

• caesarean section planned at 38 weeks after 2 antenatal injections of 12 mg of betamethasone 48 h before.

• caesarean section planned at 39 weeks without corticosteroid.

The aim is to demonstrate that programming caesarean section at 38 weeks of pregnancy, after antenatal corticosteroid, allows to avoid caesarean section in emergency (because of a labour before 39 weeks), without increasing the neonatal respiratory distress rate.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Strasbourg, France
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate

Criteria

Inclusion Criteria:

• woman who needs elective caesarean section

Exclusion Criteria:

• multiple pregnancy

• toxaemia

• rhesus immunization

• fetal infection

• maternal gastro-duodenal ulcer

• mother HIV+

• prior injection of corticosteroid during the pregnancy