CRF - Nociceptin Receptor Interactions

• Status: Completed
• Trial end date: 2019-06-01

Summary

To determine if [C-11]NOP-1A receptor binding (VT) can be altered by an intravenous hydrocortisone (cortisol) challenge through CRF-NOP interactions

• Phase: Early Phase 1

Details

• Lead Sponsor: University of Pittsburgh
• Collaborator: National Institute on Drug Abuse (NIDA)
• Treatments: Corticotropin-Releasing Hormone; Cortisol succinate; Hydrocortisone; Hydrocortisone 17-butyrate 21-propionate; Hydrocortisone acetate; Nociceptin; Nocistatin