Overview

CREON for the Treatment of Post-RYGB Hypoglycemia

Status:
Terminated
Trial end date:
2018-01-31
Target enrollment:
Participant gender:
Summary
Hypoglycemia is an increasingly recognized complication of Roux-en-Y gastric bypass (RYGB) that is poorly understood and difficult to treat. Investigators hypothesize that after RYGB some patients have incomplete carbohydrate absorption in the small intestine which leads to inconsistent glucose levels and hypoglycemia during oral consumption of a meal. Investigators further hypothesize that pancreatic enzyme supplementation with (Creon) during meals and snacks will improve carbohydrate absorption and lead to more stable glucose levels in patients with post-RYGB hypoglycemia.
Phase:
Phase 1
Details
Lead Sponsor:
East Carolina University
Treatments:
Pancreatin
Pancrelipase