COmparison Erect SPINE in Cardiac Surgery (COESPINE)
Status:
Not yet recruiting
Trial end date:
2021-04-01
Target enrollment:
Participant gender:
Summary
Open cardiac surgeries are characterized by the increased use of opioids and longer
extubation times, being post-sternotomy pain one of the causes of greater patient discomfort,
plexus blockages have been used more frequently given the good results of anatomical studies
and case series that are just beginning to be published. however, there is not enough data to
convince the scientific community of its advantages, continuing to carry out its performance
due to lack of evidence. Dexamethasone also shows an excellent result blocking the
inflammatory chain and it was evidenced that it prolongs the time of blockages when used
perineurally in the plexus blockages. This study wants to show the improvement of pain in
patients who undergo this type of surgery and also show the advantages of a longer blockage,
which can reduce the congestions of analgesic and opioids, as well as decrease the time of
hospitalization This is a double-blinded, randomized, clinical trial designed to determine
the efficacy of spine erector whit dexamethasone gives more duration of the blockage and less
pain after cardiac surgery.
Phase:
Phase 3
Details
Lead Sponsor:
Instituto do Coracao
Treatments:
Anesthetics Anesthetics, Local BB 1101 Dexamethasone Dexamethasone acetate Ropivacaine