Overview

CMV CTLs in Neonates With CMV Infection

Status:
Not yet recruiting
Trial end date:
2026-10-31
Target enrollment:
Participant gender:
Summary
Patients with moderate or severe CMV disease less than 21 days old who have a maternal donor who has a CMV response to the peptivators will be screened. All patients will receive treatment with valganciclovir or ganciclovir. There is a safety run in with treatment with CMV CTLs in cohort 1 and if found to be safe, will proceed to cohort 2 for randomization to receive antiviral therapy with or without CMV CTLs.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
New York Medical College
Treatments:
Antiviral Agents
Ganciclovir
Valganciclovir