Overview

CD19-Specific T Cells Post AlloSCT

Status:
Terminated
Trial end date:
2021-05-27
Target enrollment:
Participant gender:
Summary
This phase I trial investigates the side effects and best dose of CD19 positive (+) specific CAR-T cells in treating patients with CD19+ lymphoid malignancies, such as acute lymphoblastic leukemia, non-Hodgkin lymphoma, small lymphocytic lymphoma, or chronic lymphocytic lymphoma. Sometimes researchers change the genetic material in the cells of a patient's T cells using a process called gene transfer. Researchers then inject the changed T-cells into the patient's body. Receiving the T-cell infusion may help to control the disease.
Phase:
Phase 1
Details
Lead Sponsor:
M.D. Anderson Cancer Center
Collaborators:
Precigen, Inc
Ziopharm Oncology
Treatments:
Cyclophosphamide
Fludarabine
Fludarabine phosphate