Overview

CART-38 in Adult AML and MM Patients

Status:
Not yet recruiting
Trial end date:
2040-09-01
Target enrollment:
Participant gender:
Summary
This is an open-label Phase 1 study to estimate the safety and manufacturing feasibility of lentivirally transduced T cells expressing anti-CD38 chimeric antigen receptors expressing tandem TCRζ and 4-1BB (TCRζ /4-1BB) costimulatory domains in patients with Acute Myeloid Leukemia and Multiple Myeloma. This CAR T cell product will be referred to as "CART-38 cells".
Phase:
Phase 1
Details
Lead Sponsor:
University of Pennsylvania
Treatments:
Fludarabine