Busulfan and Fludarabine Before Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as busulfan and fludarabine, work in different
ways to stop the growth of cancer cells, either by killing the cells or by stopping them from
dividing. Giving chemotherapy with a peripheral stem cell or bone marrow transplant may allow
more chemotherapy to be given so that more cancer cells are killed. Sometimes the
transplanted cells from a donor can make an immune response against the body's normal cells.
Tacrolimus and methotrexate may stop this from happening.
PURPOSE: This phase II trial is studying how well giving busulfan together with fludarabine
before donor stem cell transplant works in treating patients with hematologic cancer.