This is a residential study that looks at the effects of buprenorphine in persons who abuse
but are not dependent on opioids. Animal studies show that very high doses of buprenorphine
produce less effects than mid-range doses. This suggests that buprenorphine can be a very
safe medication. However, no studies in humans have tested higher doses in a similar way. The
goal of this study is to show the effects of single doses of buprenorphine, across a range of
doses, in persons who are not physically dependent on opioids (but do abuse opioids).
Phase:
Phase 2
Details
Lead Sponsor:
Johns Hopkins University National Institute on Drug Abuse (NIDA)