Buprenorphine as a Treatment for Individuals Dependent on Analgesic Opioids

• Status: Completed
• Trial end date: 2005-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Opioids used to treat chronic pain have a high abuse potential. The purpose of this study is to determine the effectiveness of buprenorphine in treating opioid dependent individuals who abuse opioids that are prescribed for chronic pain.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute on Drug Abuse (NIDA)
• Collaborator: University of Texas
• Treatments: Analgesics, Opioid; Buprenorphine

Criteria

Inclusion Criteria:

• Current opioid analgesic dependence

• History of at least 2 years of oral opiate analgesic use

• Prescribed opioids for chronic pain

• Pain episode of at least 6 months duration within the 5 years prior to study entry

• Available for the duration of the study

• Good general health

Exclusion Criteria:

• Currently using any illicit substance

• Meets criteria for alcohol dependence

• History of heroin use

• History of opiate replacement therapy, including Levo-Alpha Acetyl Methadol (LAAM) or methadone

• Evidence of current maximal primary pain