A placebo-controlled and double-blind study is planned according to current legislation and
ICH GCP guidelines with 80 patients at Nordland Hospital, Bodø. Fifty percent are randomized
to receive bupivacaine 5 mg / ml on the gauze swabs used to stop the bleeding after
tonsillectomy, and 50% receive 0.9% sodium chloride.
Pain at rest and pain when swallowing according to numerical rating scale (0-10), as well as
the presence of the following symptoms (yes / no): nausea, vomiting, food intake, bleeding,
fever, need for extra painkillers in the form of morphine or similar will be registered 1, 2,
3, 4, 5, 6 hours and 1, 2 4 and 6 days after the operation. Differences are analyzed with
"mixed models" statistics and the results will be published in a peer-based journal.