Buffered Lidocaine in the Pediatric Dental Patient
Status:
Recruiting
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
Local anesthetic buffered with sodium bicarbonate has been suggested to reduce pain,
discomfort and onset time of local anesthesia on injection into tissue, compared to
non-buffered solutions. Buffered local anesthesia has been used in medicine, however
intraoral injections with buffered solutions are less common in dentistry. Most research has
focused on adult perception of pain on administration of buffered local anesthetic. There
have been few studies and inconclusive evidence to show that buffered lidocaine reduces the
perception of pain on administration in children. The purpose of this interventional study is
to assess pain reduction and onset time on injection of buffered 2% lidocaine with 1:100,000
epinephrine in children.