This is a clinical trial to evaluate the use of peritumoral injection of near-infrared dye
indocyanine green to identify lung lesions and sentinel lymph nodes. The primary purpose is
to determine if the use of ICG injected via navigational bronchoscopy, CT-guided or
transthoracic allows us to identify the first lymph node that drains from the tumor, and thus
would be the most likely site for metastatic disease, and remove it for analysis to improve
the ability to detect tumor in this node and to remove this additional site that potentially
contains tumor cells. Using this intraoperative imaging technique, we aim to improve the
identification of lung nodules for resection and the intraoperative identification of
sentinel lymph nodes in the event that a lymphadenectomy is performed.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Brigham and Women's Hospital Massachusetts General Hospital
Collaborators:
Brigham and Women's Hospital Society of University Surgeons