Overview

Brentuximab Vedotin and Imatinib in Patients With Relapsed or Refractory ALK+ ALCL

Status:
Active, not recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
This is an open label pilot study of combining BV in a licensed indication with imatinib in patients with ALCL. It is intended as a "window of opportunity" trial in which the study drugs will be given as an initial substitute for conventional chemotherapy with the intention to achieve a remission enabling the patients to proceed to autologous or allogeneic stem cell transplantation, if eligible.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Arbeitsgemeinschaft medikamentoese Tumortherapie
Treatments:
Antibodies, Monoclonal
Brentuximab Vedotin
Imatinib Mesylate