Overview

Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas

Status:
Terminated
Trial end date:
2018-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate how safe and effective the combination of two different drugs (brentuximab vedotin and rituximab) is in patients with certain types of lymphoma. This study is for patients who have a type of lymphoma that expresses a tumor marker called CD30 and/or a type that is associated with the Epstein-Barr virus (EBV-related lymphoma) and who have not yet received any treatment for their cancer, except for dose-reduction or discontinuation (stoppage) of medications used to prevent rejection of transplanted organs (for those patients who have undergone transplantation). This study is investigating the combination of brentuximab vedotin and rituximab as a first treatment for lymphoma patients
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Northwestern University
Collaborators:
Seagen Inc.
Seattle Genetics, Inc.
Treatments:
Antibodies
Antibodies, Monoclonal
Brentuximab Vedotin
Immunoconjugates
Immunoglobulins
Rituximab