The primary objective of this study is to determine the effects of the antiprogestin
ulipristal acetate (UA) on the epithelial and stromal compartments of the normal breast in
women at increased risk of breast cancer (BC) and to relate these effects to quantitative
changes on multiparametric magnetic resonance imaging (MRI). The goal is to define predictive
imaging biomarkers for subsequent testing in randomised prevention trials of antiprogestins.
Phase:
Phase 2
Details
Lead Sponsor:
Manchester University NHS Foundation Trust University Hospital of South Manchester NHS Foundation Trust