Brain Effects of Opiate Agonist and Antagonist

• Status: Completed
• Trial end date: 2019-04-16
• Target enrollment: 0
• Participant gender: All

Summary

This study will look at the short-term effect of morphine on brain response to food.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Rochester
• Treatments: Morphine

Criteria

Inclusion Criteria:

• Healthy participants

• Patients in pain: suffering from persistent pain more days than not, 3/10 in intensity on a numerical rating scale, for at least 6 weeks or more.

Exclusion Criteria:

• Any DSM diagnosis

• diabetes

• food allergies

• lactose intolerance

• participants seeking to quit smoking or to lose weight

• participants on any psychotropic medication including opiate based analgesics (e.g. oxycodone, methadone, suboxone)

• pregnant or nursing women

• pacemaker or other implanted electrical devices

• Participants with a past history of head trauma or seizures

• Any past history of illegal drug or alcohol misuse

• Participants who cannot undergo an MRI scan.