Bradykinin Receptor Blocker in ACE Inhibitor-associated Angioedema
Status:
Terminated
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
Individuals with heart disease or high blood pressure are often prescribed angiotensin
converting enzyme (ACE) inhibitors to treat their disease. However, the use of ACE inhibitors
can be associated with angioedema, a rare but life-threatening condition that causes swelling
of the face and other body parts. This study will evaluate the effectiveness of the drug
HOE-140 at decreasing symptoms of angioedema in people taking ACE inhibitors who develop the
condition.
Phase:
Phase 1
Details
Lead Sponsor:
Vanderbilt University Vanderbilt University Medical Center