Botulinum Toxin A in the Treatment of Hemifacial Spasm

• Status: Unknown status
• Trial end date: 2018-08-31
• Target enrollment: 0
• Participant gender: All

Summary

Hemifacial spasm patients who received botulinum toxin A injection were divided into two groups. Group A received unilateral injection while group B received bilateral injection. Patients completed follow-up A researcher record facial videos and analyzed facial symmetry and completed 3 scales.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tongji University
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• clinical diagnosis of hemifacial spasm

• Scott grading III to IV

• hemifacial spasm duration of half or more years

• last botulinum toxin A application at least 3 months before the start of the study

Exclusion Criteria:

• history of facial trauma, congenital facial asymmetry, facial nerve microsurgical decompression

• bilateral hemifacial spasm

• allergies to botulinum toxin A or to any component of the drug

• previous treatment with botulinum toxin A fewer than 3 months

• the use of drugs that could interfere with neuromuscular transmission or spasm