Bosutinib in Adult Patients With Recurrent Glioblastoma
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
For many brain tumors, one reason that chemotherapy drugs might not be effective is that the
drug may not be able to get into the brain tumor and kill the cancer cells. The brain is
protected by a layer called the blood brain barrier. This barrier prevents substances from
entering. The purpose of this research study is to determine if bosutinib can get past the
blood brain barrier and into the brain tumor, and to see how well bosutinib works in killing
cancer cells.
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
Brigham and Women's Hospital Dana-Farber Cancer Institute Pfizer