Bortezomib and Gemcitabine in Treating Older Patients With Advanced Solid Tumors
Status:
Completed
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Bortezomib may stop the growth of solid tumors by blocking some of the enzymes
needed for cell growth and by blocking blood flow to the tumor. Drugs used in chemotherapy,
such as gemcitabine, work in different ways to stop the growth of tumor cells, either by
killing the cells or by stopping them from dividing. Giving bortezomib together with
gemcitabine may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of bortezomib and
gemcitabine in treating older patients with advanced solid tumors.