The goal of this clinical trial is to test whether potassium citrate improves skeletal health
in adults and children with chronic kidney disease. The main questions it aims to answer are:
- To evaluate effects of potassium citrate treatment on bone quality and strength.
- To evaluate mechanism(s) underlying the effects of potassium citrate on skeletal health.
Participants will be asked to:
- provide blood, urine and answer questions about health and diet three times during an 8
months period
- undergo advanced bone imaging with high resolution-peripheral quantitative CT scan twice
during 8 months
- take study pills for 4-6 weeks at the beginning of the study to ensure safety
- take either potassium citrate or placebo for 6 months during the blinded portion of the
study
Researchers will compare the bone imaging between the potassium citrate and the placebo
groups at the end of the study.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Albert Einstein College of Medicine
Collaborators:
Columbia University National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) University of Pittsburgh Medical Center University of Utah