Bone Mass and Strength After Kidney Transplantation

• Status: Active, not recruiting
• Trial end date: 2022-01-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test whether active vitamin D (calcitriol) protects bones from weakening and protects blood vessels from calcium deposits over the first year of kidney transplantation.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Columbia University
• Collaborator: Satellite Healthcare
• Treatments: Calcitriol; Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Age older than 18

• Self-describes as White race

Exclusion Criteria:

• Lower extremity amputations

• Non-ambulatory

• Paget´s disease of bone

• Current hyperthyroidism, untreated hypothyroidism

• Medical diseases (end stage liver, intestinal malabsorption)

• Use within the prior year pod anti-seizure medications that induce the cytochrome P450 system, testosterone, estrogen, selective estrogen receptor modulators

• Weight >300 pounds

• Dual organ transplant

• Myocardial infarction or stroke

• Tobacco use within the past year