Bone Marrow Transplantation in Treating Children With Sickle Cell Disease
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
RATIONALE: Sickle cell disease is an inherited disorder in which abnormal, crescent-shaped
red blood cells interfere with the ability of the blood to carry oxygen through the body and
can cause severe pain, stroke, and organ damage. Bone marrow transplantation, is a procedure
in which the soft, sponge-like tissue in the center of bones producing white blood cells, red
blood cells, and platelets is replaced by bone marrow from a another person. Bone marrow
transplantation may be an effective treatment in relieving the symptoms of sickle cell
disease.
PURPOSE: Phase I/II trial to study the effectiveness of bone marrow transplantation in
treating children who have sickle cell disease.