Overview

BonE and Joint Infections - Simplifying Treatment in Children Trial

Status:
Recruiting
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
This is a single centre trial of children with bone and joint infections (BJIs). The primary objective is to establish if in children with acute, uncomplicated BJIs, entirely oral antibiotic treatment is not inferior to initial intravenous (IV) treatment for 2 to 4 days followed by an oral antibiotic course in achieving full recovery 12 months after presentation. Children will be randomly allocated to the 'entirely oral antibiotic' group or the 'standard treatment' group.
Phase:
Phase 4
Details
Lead Sponsor:
Murdoch Childrens Research Institute
Treatments:
Cefazolin
Cephalexin