A multidisciplinary investigation examining the circadian mechanisms regulating
cardiovascular (CV) risk in obesity. Specifically, in a valid circadian protocol, the
investigators aim to study resting cardiovascular risk markers and the reactivity of
circadian rhythms in these risk markers to standardized stressors in obesity. Furthermore,
using an ingenious approach, the investigators propose to explore impairment in pre/post
synaptic function in the cardiac left ventricle.