Overview

Blood Levels of Local Anaesthetic in Knee Arthroplasty Using a Continuous Infusion Device

Status:
Unknown status
Trial end date:
2014-01-01
Target enrollment:
0
Participant gender:
All
Summary
The primary goal is to evaluate ropivacaine blood concentrations during and after local anaesthetic (ropivacaine) infiltration - the Caledonian technique - for total knee replacement surgery. The investigators plan to measure these levels by testing blood samples taken over a timed period. This will allow us to confirm whether the current regimen of local anaesthetic use is within safe limits.
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Golden Jubilee National Hospital
Collaborators:
B. Braun Medical Inc.
University of Strathclyde
Treatments:
Anesthetics
Anesthetics, Local
Ropivacaine
Criteria
Inclusion Criteria:

- Male or female patients greater than 65 years of age

Exclusion Criteria:

- Patients with a known sensitivity/allergy to ropivacaine or amide-type local
anaesthetics

- Patients who are not suitable for the Caledonian technique

- Patients who refuse or are unable to give consent

- Patients undergoing bilateral hip replacements

- Patients with known heart, liver or kidney failure