Blood Levels of Anti-HIV Drugs Used in Combination Regimens in HIV Infected Children
Status:
Completed
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
Limited data exist about combination anti-HIV treatment regimens in children, including how
those drugs are cleared by the body in children. The purpose of this study is to measure the
blood levels of the following combinations of anti-HIV drugs in HIV infected chilren:
tenofovir disoproxil fumurate (TDF) and efavirenz (EFV) or nevirapine (NVP); TDF and
darunavir (DRV) with or without EFV; and TDF and ritonavir (RTV) with or without EFV.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)