Overview Blocking the Effects of Serotonin to Prevent Ischemic Mitral Regurgitation: a Randomized Trial Status: Not yet recruiting Trial end date: 2027-09-01 Target enrollment: Participant gender: Summary This study is intended to investigate the effect of cyproheptadine (a 5HT2B receptor blocker) on mitral regurgitation severity. Phase: Phase 2 Details Lead Sponsor: Laval UniversityCollaborator: Canadian Institutes of Health Research (CIHR)Treatments: Cyproheptadine