Block Pressor Response to Intubation

• Status: Not yet recruiting
• Trial end date: 2024-01-31
• Target enrollment: 0
• Participant gender: Female

Summary

Laryngoscopy and endotracheal intubation are necessary for effective control of airway and ventilation, but it has deleterious effects such as hypertension and disrhythmia

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Dexmedetomidine; Lidocaine; Magnesium Sulfate

Criteria

Inclusion Criteria:

• ASA physical status I-II

• Age between 23 to 40 years

• With airway of Mallampati grade I and II

• Elective diagnostic laparoscopic gynecologic surgery under general anesthesia with endotracheal intubation

Exclusion Criteria:

• Mallampatti grading III and IV, anticipated difficult intubation

• Body mass index (BMI > 35 kg/m2), full stomach, pregnancy

• Emergency surgery

• History of cardiac or neurological disease or patient with asthma

• History of Hypersensitivity to the study drugs

• Advanced hepatic or renal failure.

• Patients in whom the duration of laryngoscopy lasted more than 20 seconds

• Patient refusal.