Bleach Bath Treatment of Adults With Atopic Dermatitis
Status:
Completed
Trial end date:
2017-06-01
Target enrollment:
Participant gender:
Summary
This is pilot, mechanistic study to address whether bleach baths given to adult subjects with
atopic dermatitis or eczema, who are colonized with the bacteria Staphylococcus aureus, will
significantly alter their skin microbiome and in so doing improve their skin barrier,
diminish expression of inflammatory proteins in the skin and improve itch. To answer these
questions the investigators will perform a 3-month, pilot, investigator-initiated,
single-center, open-label clinical study. This study will allow us to test the following
hypothesis: 1) that bleach baths will normalize skin barrier function, 2) that bleach baths
will diminish the local inflammatory response in the skin, and 3) that bleach baths will
improve validated measures of itch (also called pruritus).
Phase:
N/A
Details
Lead Sponsor:
University of Rochester
Collaborators:
National Eczema Association National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)