Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT)
Status:
Completed
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
We are doing this study to learn how genes affect the way that people, specifically Black
people, respond to treatment for asthma. Recent studies suggest that people respond
differently to some asthma medications (eg Serevent, Foradil). Some people feel better when
they use these inhalers, but others may not, and some people get worse. It seems that this
difference shows up more often in Blacks than in Whites, which is why we are looking for
Black subjects for this study. In all people, this difference seems to depend on their genes
or DNA. This study is comparing the use of long acting asthma medications (Serevent, Foradil)
to Tiotropium (Spiriva) for the treatment of asthma. Spiriva is used to treat chronic
obstructive pulmonary disease (COPD). This study will help to see if this medication is also
useful for treating asthma and whether it works better for some people than the current
asthma medications.
Phase:
Phase 3
Details
Lead Sponsor:
Brigham and Women's Hospital
Collaborators:
American Academy of Family Physicians National Research Network Baim Institute for Clinical Research Harvard Clinical Research Institute Olmsted Medical Center