Black Cohosh Extract in Postmenopausal Breast Health

• Status: Completed
• Trial end date: 2007-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of the study is to determine if black cohosh extract (BCE) administration in symptomatic postmenopausal women results in estrogenic stimulation of the breast, as determined by estradiol, pS2, FSH, LH, and PSA levels in nipple aspirate fluid.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Center for Complementary and Integrative Health (NCCIH)
• Collaborator: University of Missouri-Columbia

Criteria

• Postmenopausal females

• 20 months since any breastfeeding

• Active postmenopausal symptoms, i.e., hot flashes

• At least 6 months since last menstrual period or have had a hysterectomy with both ovaries removed

• Able to make 4 visits during the trial to the study clinic in Columbia, Missouri