Bispectral Index-guided Sedation for Flexible Bronchoscopy
Status:
Completed
Trial end date:
2009-09-01
Target enrollment:
Participant gender:
Summary
With the advances of flexible bronchoscopy, like metallic stent, electrocautery and real time
endobronchial ultrasound, the complexity and duration of procedures are increasing. So,
adequate sedation and analgesia is important for both patients and bronchoscopist.
Clinical-judged midazolam administration is the current standard. However, midazolam is
difficult to titrated and the clinical observations are not reliable sedative indices.
Propofol is titrated easily because of its unique pharmacokinetics. Bispectral index (BIS), a
real time monitor of depth-of-sedation, has been applied in general anesthesia.
We design a BIS-guided propofol sedation for bronchoscopy. Through the combination of
advantages of propofol and BIS, we hope to provide patients a more tolerable and safety
sedation for bronchoscopy.