Bispectral Index and Clinical Parameters Evaluation in Dental Procedures
Status:
Completed
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
BACKGROUND: The degree of consciousness during nitrous oxide use is still a matter of concern
for both dentists and anesthesiologists. Investigators hypothesized that BIS levels do not
vary according nitrous oxide concentration during minimum to moderate sedation in the dental
treatment.
METHODS: One hundred patients undergoing dental procedures demanding local anesthesia (1.8 mL
of 2% lidocaine with 1:100.000 epinephrine) were enrolled in this study. Initial pain and
anxiety were measured by 11-point numerical and anxiety visual scales, respectively.
Systolic/diastolic arterial blood pressure, SpO2, heart and respiratory rates, and
psychomotor ability (Trieger test) were assessed before, during and after dental treatment.
Sedation levels were evaluated by both BIS and sedation analogic scale at the same intervals.
The duration of treatment along with nitrous oxide concentration and side effects were
observed. Kruskal-Wallis, Friedman and Mann-Whitney tests were used (alpha=5%).
Phase:
Phase 4
Details
Lead Sponsor:
Francisco Groppo
Collaborators:
Faculty Sao Leopoldo Mandic Campinas pontifical catholic university - Rio de Janeiro