Biphasic Effects of Different Doses Ephedrine on Hemodynamics in Elderly Patients Under General Anesthesia
Status:
Recruiting
Trial end date:
2022-07-30
Target enrollment:
Participant gender:
Summary
Ephedrine is commonly clinically vasoactive drugs, which can constrict blood vessels and
increase blood pressure. Ephedrine can not only stimulate α receptors, but also β receptors,
that's to say, it can increase heart rate, stroke volume, and cardiac output, but it also can
decrease the level of systemic vascular resistance. This research aims to observe the
short-term vasodilator effect of diffierent doses of ephedrine used in elderly patients under
general anesthesia in clinical practice, and analyze the main reasons for this phenomenon and
take preventive actions to minimize the possibility of further lowering of blood pressure to
provide references for clinical rational use of drugs.