Biomarkers of Neuroinflammation and Anti-Inflammatory Treatments in Major Depressive Disorder
Status:
Completed
Trial end date:
2019-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if translocator protein total distribution volume
(TSPO VT) is elevated in major depressive disorder that is not responding to medication and
if adding minocycline can affect TSPO VT. Many remain treatment resistant with common
antidepressant treatments and the investigators think it may be due to poor targeting of
brain pathologies.