Biological Effect of Vitamin D in Patients With Urothelial Carcinoma
Status:
Recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
The study population will be 50 women or men diagnosed with urothelial cancer candidates to
undergo cystectomy as part of their antitumor treatment. The main objective of the study is
to determine the biological effect of Vitamin D on tumor tissue phenotype; for thus, all
subjects enrolled in the study will take Vitamin D supplementation 4 weeks prior undergoing
surgery. Urothelial tissue will be obtained from the surgical procedure and will be studied
for the Vitamin D effect on cancer cell, compared with that urothelial tissue biopsy obtained
in the moment of cancer diagnosis.
Phase:
Phase 4
Details
Lead Sponsor:
Germans Trias i Pujol Hospital
Collaborators:
Centro Nacional de Investigaciones Oncologicas CARLOS III Fundació Institut Germans Trias i Pujol Spanish Clinical Research Network - CAIBER Spanish Clinical Research Network - SCReN
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins