Overview

Biologic Tapering Study of TNF Inhibitors in Axial Spondyloarthritis

Status:
Not yet recruiting
Trial end date:
2022-11-30
Target enrollment:
Participant gender:
Summary
Current evidence on tapering of tumor necrosis factor inhibitors (TNFi) in axial spondyloarthritis (axSpA) is still hampered by heterogeneity in tapering regimens, selection and performance biases, and lack of data on optimized treatment dosing strategies especially in real-world clinical settings. This study aims to contribute to the ongoing investigation of disease-activity-guided tapering of TNFi in axSpA in the form of a prospective, randomized controlled trial.
Phase:
Phase 4
Details
Lead Sponsor:
University Health Network, Toronto
Treatments:
Adalimumab
Antibodies, Monoclonal
Certolizumab Pegol
Etanercept
Golimumab
Infliximab