Bioequivalence And Food Effect Study Of Bosutinib In Healthy Subjects
Status:
Completed
Trial end date:
2011-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to demonstrate the bioequivalence of the clinical tablet
formulation (100 mg x 5) to the clinical capsule formulation (100 mg x 5) in healthy subjects
under fed condition (Cohort 1) and to investigate the effect of a high-fat meal on the
pharmacokinetics of bosutinib after administration of the proposed commercial tablet
formulation (100 mg x 4) in healthy subjects (Cohort 2).